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Voruciclib

Catalog No.: 178306
Cas No.: 1000023-04-0
Purity : 98.0%
178306 - Voruciclib | CAS 1000023-04-0

Catalog number : 178306

CAS number : 1000023-04-0

分子式 : C22H19ClF3NO5

分子量 : 469.8412

Iupac 化学名称 : 2-(2-Chloro-4-(trifluoromethyl)phenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-1-benzopyran-4-one

Smile : ClC1=C(C=CC(=C1)C(F)(F)F)C=1OC2=C(C(C1)=O)C(=CC(=C2[C@H]2[C@@H](N(CC2)C)CO)O)O

InChiKey : MRPGRAKIAJJGMM-OCCSQVGLSA-N

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同义词P1446A05, P1446A-05, P1446A 05, Voruciclib.
英文同义词P1446A05, P1446A-05, P1446A 05, Voruciclib.
分子式C22H19ClF3NO5
分子量469.8412
外观类白色至白色固体
纯度98.0%
可溶性可溶于DMSO;不溶于水
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileClC1=C(C=CC(=C1)C(F)(F)F)C=1OC2=C(C(C1)=O)C(=CC(=C2[C@H]2[C@@H](N(CC2)C)CO)O)O
InChiKeyMRPGRAKIAJJGMM-OCCSQVGLSA-N
InChiInChI=1S/C22H19ClF3NO5/c1-27-5-4-12(14(27)9-28)19-15(29)7-16(30)20-17(31)8-18(32-21(19)20)11-3-2-10(6-13(11)23)22(24,25)26/h2-3,6-8,12,14,28-30H,4-5,9H2,1H3/t12-,14+/m1/s1
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Voruciclib,又称P1446A-05,是一种蛋白质激酶抑制剂,专门针对细胞周期依赖性激酶4(CDK4),具有潜在的抗肿瘤活性。

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