Vigabatrin, also known as gamma-vinyl-GABA, is an antiepileptic drug that inhibits the breakdown of -aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA receptors. Vigabatrin is an irreversible suicide inhibitor of gamma-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the catabolism of GABA, which increases the level of GABA in the brain. Vigabatrin is a racemic compound, and its [S]-enantiomer is pharmacologically active.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Vigabatrin |
| Iupac 化学名称 | 4-aminohex-5-enoic acid |
| 同义词 | CPP109; CPP-109; CPP 109; RMI 71754; RMI71754; RMI-71754; MDL 71754; MDL-71754; MDL71754; Vigabatrin; gamma-vinyl-GABA, brand name Sabril, Sabrilex. |
| 英文同义词 | CPP109; CPP-109; CPP 109; RMI 71754; RMI71754; RMI-71754; MDL 71754; MDL-71754; MDL71754; Vigabatrin; gamma-vinyl-GABA, brand name Sabril, Sabrilex. |
| 分子式 | C6H11NO2 |
| 分子量 | 129.159 |
| Smile | NC(CCC(=O)O)C=C |
| InChiKey | PJDFLNIOAUIZSL-UHFFFAOYSA-N |
| InChi | InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9) |
| Cas号 | 60643-86-9 |
| 相关CAS号 | |
| 外观性状 | crystalline solid |
| 纯度 | 98% |
| 存储 | 3 years -20ºCpowder |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 | |
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