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Venetoclax(ABT-199)

Catalog No.: 60101
Cas No.: 1257044-40-8
Purity : 98%

Venetoclax, formerly known as ABT-199(GDC-0199), is a Bcl-2-selective inhibitor with Ki

For research use only. We do not sell to patients.

Chemical Information

名称Venetoclax(ABT-199)
Iupac 化学名称2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
同义词Venetoclax;ABT-199;GDC-0199
英文同义词Venetoclax;ABT-199;GDC-0199
分子式C45H50ClN7O7S
分子量868.44
SmileN1C=CC=2C1=NC=C(C2)OC2=C(C(=O)NS(=O)(=O)C1=CC(=C(C=C1)NCC1CCOCC1)[N+](=O)[O-])C=CC(=C2)N2CCN(CC2)CC2=C(CC(CC2)(C)C)C2=CC=C(C=C2)Cl
InChiKeyLQBVNQSMGBZMKD-UHFFFAOYSA-N
InChiInChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)
Cas号1257044-40-8
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Ordering Information

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Formulationcrystalline solid
纯度98%
存储3 years -20℃powder
可溶性DMSO 100 mg/ml; water <1 mg/ml
Handling
运输条件Shipped under ambient temperature as non-hazardous chemical.
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

60101 - Venetoclax(ABT-199) | CAS 1257044-40-8

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