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Vatalanib

Catalog No.: 010434
Cas No.: 212141-54-3
Purity : 98% 
010434 - Vatalanib | CAS 212141-54-3

Catalog number : 010434

CAS number : 212141-54-3

分子式 : C20H15ClN4 

分子量 : 346.813 

Iupac 化学名称 : N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine 

Smile : C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4

InChiKey : YCOYDOIWSSHVCK-UHFFFAOYSA-N

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同义词PTK787; PTK/ZK; CGP-79787; ZK-222584 
英文同义词PTK787; PTK/ZK; CGP-79787; ZK-222584 
分子式C20H15ClN4 
分子量346.813 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileC1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4
InChiKeyYCOYDOIWSSHVCK-UHFFFAOYSA-N
InChiInChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)
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Vatalanib free base is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. 

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