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VX-702

Catalog No.: 16070804
Cas No.: 745833-23-2
Purity : 98% by HPLC 
16070804 - VX-702 | CAS 745833-23-2

Catalog number : 16070804

CAS number : 745833-23-2

分子式 : C19H12F4N4O2 

分子量 : 404.31779 

Iupac 化学名称 : 6-[(Aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide 

Smile : NC(=O)N(C1=CC=C(C(=N1)C1=C(C=C(C=C1)F)F)C(=O)N)C1=C(C=CC=C1F)F

InChiKey : FYSRKRZDBHOFAY-UHFFFAOYSA-N

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同义词VX702; VX 702 
英文同义词VX702; VX 702 
分子式C19H12F4N4O2 
分子量404.31779 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileNC(=O)N(C1=CC=C(C(=N1)C1=C(C=C(C=C1)F)F)C(=O)N)C1=C(C=CC=C1F)F
InChiKeyFYSRKRZDBHOFAY-UHFFFAOYSA-N
InChiInChI=1S/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29)
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VX-702, one of a series of second-generation, is an orally active p38 MAP kinase inhibitors, for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases. VX-702 prevents activation of p38MAPK and decrements in many platelet storage parameters after exposure to 16 C without agitation for 24 h.  

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