VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP transcriptional activity.
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| 名称 | VT-3989 |
|---|---|
| Iupac 化学名称 | N-[(2R)-1-Hydroxypropan-2-yl]-5-[4-(trifluoromethyl)phenoxy]naphthalene-2-carboxamide |
| 同义词 | VT-3989 ; VT 3989 ; VT3989 |
| 英文同义词 | VT-3989 ; VT 3989 ; VT3989 |
| 分子式 | C21H18F3NO3 |
| 分子量 | 389.37 |
| Smile | O=C(C1=CC=C2C(OC3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C)CO |
| InChiKey | FJIVCOAHSKDOAC-CYBMUJFWSA-N |
| InChi | InChI=1S/C21H18F3NO3/c1-13(12-26)25-20(27)15-5-10-18-14(11-15)3-2-4-19(18)28-17-8-6-16(7-9-17)21(22,23)24/h2-11,13,26H,12H2,1H3,(H,25,27)/t13-/m1/s1 |
| Cas号 | 2506273-81-8 |
| 相关CAS号 | 2506273-81-8 |
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Solid powder |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| 可溶性 | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| 处理方式 | Refer to MSDS |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| 海关编码 | 2934200090 |
| Targets | YAP/TAZ Inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |