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VR23

Catalog No.: 120423
Cas No.: 1624602-30-7
Purity : 98% 
120423 - VR23 | CAS 1624602-30-7

Catalog number : 120423

CAS number : 1624602-30-7

分子式 : C19H16ClN5O6S 

分子量 : 477.876 

Iupac 化学名称 : 7-chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline 

Smile : O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C32)CC1)(C4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)=O

InChiKey : PDQVZPPIHADUOO-UHFFFAOYSA-N

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同义词VR-23; VR 23 
英文同义词VR-23; VR 23 
分子式C19H16ClN5O6S 
分子量477.876 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileO=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C32)CC1)(C4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)=O
InChiKeyPDQVZPPIHADUOO-UHFFFAOYSA-N
InChiInChI=1S/C19H16ClN5O6S/c20-13-1-3-15-16(11-13)21-6-5-17(15)22-7-9-23(10-8-22)32(30,31)19-4-2-14(24(26)27)12-18(19)25(28)29/h1-6,11-12H,7-10H2
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VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM) and caspase-like proteasomes (IC50 = 3 M). 

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