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VLX1570

Catalog No.: 611932
Cas No.: 1431280-51-1
Purity : 98% 

VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM.

VLX1570 inhibits proteasome deubiqu-itinase activity and induces accumulation of high molecularweight  polyubiquitinated proteins in cells.
Knock-down of USP14 in multiple myeloma cells induces loss of cell viability
VLX1570 induces accumulation of polyubiquitin chains and elicits apoptosis of multiple myeloma cells
VLX1570 induces apoptosis and cell death of MM cells


 

For research use only. We do not sell to patients.

Chemical Information

名称VLX1570
Iupac 化学名称VLX1570 
同义词VLX 1570; VLX-1570 
英文同义词VLX 1570; VLX-1570 
分子式C23H17F2N3O6 
分子量469.39 
InChiKey
InChi
Cas号1431280-51-1
Related CAS

Ordering Information

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Formulationcrystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

611932 - VLX1570 | CAS 1431280-51-1

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