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VLX1570

编号: 611932
Cas号: 1431280-51-1
纯度: 98% 

VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM.

VLX1570 inhibits proteasome deubiqu-itinase activity and induces accumulation of high molecularweight  polyubiquitinated proteins in cells.
Knock-down of USP14 in multiple myeloma cells induces loss of cell viability
VLX1570 induces accumulation of polyubiquitin chains and elicits apoptosis of multiple myeloma cells
VLX1570 induces apoptosis and cell death of MM cells


 

仅供研究使用。 我们不向患者出售。

化学信息

名称VLX1570
Iupac 化学名称VLX1570 
同义词VLX 1570; VLX-1570 
英文同义词VLX 1570; VLX-1570 
分子式C23H17F2N3O6 
分子量469.39 
InChiKey
InChi
Cas号1431280-51-1
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

611932 - VLX1570 | CAS 1431280-51-1

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