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Uprosertib (GSK2141795)

Catalog No.: 16070901
Cas No.: 1047634-65-0
Purity : 98% by HPLC 
16070901 - Uprosertib (GSK2141795) | CAS 1047634-65-0

Catalog number : 16070901

CAS number : 1047634-65-0

分子式 : C18H16Cl2F2N4O2 

分子量 : 429.25 

Iupac 化学名称 : 2-Furancarboxamide, N-[(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)- 

Smile : NC[C@H](CC1=CC(=C(C=C1)F)F)NC(=O)C=1OC(=C(C1)C1=C(C=NN1C)Cl)Cl

InChiKey : AXTAPYRUEKNRBA-JTQLQIEISA-N

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同义词GSK795 
英文同义词GSK795 
分子式C18H16Cl2F2N4O2 
分子量429.25 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileNC[C@H](CC1=CC(=C(C=C1)F)F)NC(=O)C=1OC(=C(C1)C1=C(C=NN1C)Cl)Cl
InChiKeyAXTAPYRUEKNRBA-JTQLQIEISA-N
InChiInChI=1S/C18H16Cl2F2N4O2/c1-26-16(12(19)8-24-26)11-6-15(28-17(11)20)18(27)25-10(7-23)4-9-2-3-13(21)14(22)5-9/h2-3,5-6,8,10H,4,7,23H2,1H3,(H,25,27)/t10-/m0/s1
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Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively 

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