乌苯美司
编号: 17030602
Cas号: 58970-76-6
纯度: 98%
Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.
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化学信息
| 名称 | 乌苯美司 |
|---|---|
| Iupac 化学名称 | ((2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl)-L-leucine |
| 同义词 | Ubenimex; NK 421; NK-421; NK421; Bestatin; NSC 265489 |
| 英文同义词 | Ubenimex; NK 421; NK-421; NK421; Bestatin; NSC 265489 |
| 分子式 | C16H24N2O4 |
| 分子量 | 308.378 |
| Smile | N[C@@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)O)O)CC1=CC=CC=C1 |
| InChiKey | VGGGPCQERPFHOB-RDBSUJKOSA-N |
| InChi | InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 |
| Cas号 | 58970-76-6 |
| 相关CAS号 |
订购信息
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