UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | UNC-2025 |
| Iupac 化学名称 | (1r,4r)-4-(2-(butylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol |
| 同义词 | UNC-2025; UNC2025; UNC 2025 |
| 英文同义词 | UNC-2025; UNC2025; UNC 2025 |
| 分子式 | C28H40N6O |
| 分子量 | 476.66 |
| InChiKey | |
| InChi | |
| Cas号 | 1429881-91-3 |
| 相关CAS号 | |
| 外观性状 | White solid powder |
| 纯度 | 97% |
| 存储 | -20 ºC for 3 years |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |