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UF-010

Catalog No.: 16122842
Cas No.: 537672-41-6
Purity : 98% 
16122842 - UF-010 | CAS 537672-41-6

Catalog number : 16122842

CAS number : 537672-41-6

分子式 : C11H15BrN2O 

分子量 : 271.158 

Iupac 化学名称 : UF-010 

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同义词UF-010; UF 010; UF010 
英文同义词UF-010; UF 010; UF010 
分子式C11H15BrN2O 
分子量271.158 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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UF-010 is a Class I HDAC inhibitor (IC50 values are 0.06, 0.1, 0.5 and 1.5 M for HDACs 3, 2, 1 and 8, respectively). UF010 inhibits cancer cell proliferation via class I HDAC inhibition. This causes global changes in protein acetylation and gene expression, resulting in activation of tumor suppressor pathways and concurrent inhibition of several oncogenic pathways. The isotype selectivity coupled with interesting biological activities in suppressing tumor cell proliferation support further preclinical development of the UF010 class of compounds for potential therapeutic applications. 

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