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Trilaciclib (G1T28)

编号: 185235
Cas号: 1374743-00-6
纯度: >98%

Trilaciclib是一种小分子竞争性细胞周期蛋白依赖性激酶4和6(CDK4 / 6)抑制剂,具有潜在的抗肿瘤活性。

TRILACICLIB (G1T28), 现货, contact us by email for the Bulk quotation.

仅供研究使用。 我们不向患者出售。

化学信息

名称Trilaciclib (G1T28)
Iupac 化学名称2'-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one
同义词G1T28 ; G1T-28 ; G1T 28 ; Trilaciclib.
英文同义词G1T28 ; G1T-28 ; G1T 28 ; Trilaciclib.
分子式C24H30N8O
分子量446.559
SmileO=C1NCC2(N3C1=CC4=CN=C(NC5=NC=C(N6CCN(C)CC6)C=C5)N=C43)CCCCC2
InChiKeyPDGKHKMBHVFCMG-UHFFFAOYSA-N
InChiInChI=1S/C24H30N8O/c1-30-9-11-31(12-10-30)18-5-6-20(25-15-18)28-23-26-14-17-13-19-22(33)27-16-24(7-3-2-4-8-24)32(19)21(17)29-23/h5-6,13-15H,2-4,7-12,16H2,1H3,(H,27,33)(H,25,26,28,29)
Cas号1374743-00-6
相关CAS号1374743-00-6(Free base) ; 1977495-97-8 (2HCl)

订购信息

包装价格库存纯度备货期
大货询价询价询价
Request Bulk Quote Download MSDS 电话 : +86-177 0271 9238   Email : sales@sun-shinechem.com
外观性状 类白色至白色固体
纯度>98%
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO
处理方式Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
运输条件可在常温下运输
海关编码2933999701
Targetsintravenous CDK4/6 inhibitor
MechanismTRILACICLIB (G1T28), A HIGHLY POTENT, TRANSIENT CDK 4/6 INHIBITOR WITH IC50s OF 1 nM AND 4 nM FOR CDK4 AND CDK6, RESPECTIVELY, HAS THE POTENTIAL TO DECREASE MYELOTOXICITY AND IMPROVE ANTI-TUMOR EFFICACY.
Cell study
Animal study
Clinical study
Not available

化学结构

185235 - Trilaciclib (G1T28) | CAS 1374743-00-6

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