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Tenapanor

Catalog No.: 122919
Cas No.: 1234423-95-0
Purity : 98% 

Tenapanor is an inhibitor of the sodium-proton exchanger NHE3. This antiporter protein is found in the kidney and intestines, and normally acts to regulate the levels of sodium absorbed and secreted by the body. When administered orally, tenapanor selectively inhibits sodium uptake in the intestines, limiting the amount absorbed from food, and thereby reduces levels of sodium in the body. This may make it useful in the treatment of chronic kidney disease and hypertension, both of which are exacerbated by excess sodium in the diet.

Tenapanor, Bulk in stock, contact us by email for the quotation. Kg scale intermediates are also be provided by custom synthesis.

For research use only. We do not sell to patients.

Chemical Information

名称Tenapanor
Iupac 化学名称1-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethylcarbamoylamino]butyl]urea 
同义词AZD1722 ; RDX5791 ; AZD-1722 ; RDX-5791 ; AZD 1722
英文同义词AZD1722 ; RDX5791 ; AZD-1722 ; RDX-5791 ; AZD 1722
分子式C50H66Cl4N8O10S2 
分子量1145.049 
SmileO=S(C1=CC=CC([C@@H]2CN(C)CC3=C2C=C(Cl)C=C3Cl)=C1)(NCCOCCOCCNC(NCCCCNC(NCCOCCOCCNS(=O)(C4=CC=CC([C@@H]5CN(C)CC6=C5C=C(Cl)C=C6Cl)=C4)=O)=O)=O)=O
InChiKeyDNHPDWGIXIMXSA-CXNSMIOJSA-N
InChiInChI=1S/C50H66Cl4N8O10S2/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)58-14-18-70-22-24-72-20-16-60-74(67,68)40-10-6-8-36(26-40)44-32-62(2)34-46-42(44)28-38(52)30-48(46)54/h5-10,25-30,43-44,59-60H,3-4,11-24,31-34H2,1-2H3,(H2,55,57,63)(H2,56,58,64)/t43-,44-/m0/s1
Cas号1234423-95-0
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Ordering Information

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Formulation类白色至白色固体
纯度98% 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

122919 - Tenapanor | CAS 1234423-95-0

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