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Telotristat ethyl

编号: 17011722
Cas号: 1033805-22-9
纯度: 98% 

Telotristat ethyl, also known as LX 1032 or LX 1606, is an oral serotonin synthesis inhibitor or peripheral tryptophan hydroxylase (TPH) inhibitor . Telotristat etiprate has activity in controlling diarrhea associated with carcinoid syndrome. LX1606 acts by inhibiting the enzyme tryptophan hydoxylase (TPH) and reduces serotonin production both inside and outside the GI tract without affecting brain serotonin levels. TPH is the rate-limiting enzyme involved in serotonin biosynthesis and is present in metastatic carcinoid tumor cells. 

仅供研究使用。 我们不向患者出售。

化学信息

名称Telotristat ethyl
Iupac 化学名称ethyl (S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate 
同义词LX 1032; LX-1032; LX1032; LX 1606; LX1606; LX-1606 
英文同义词LX 1032; LX-1032; LX1032; LX 1606; LX1606; LX-1606 
分子式C27H26ClF3N6O3 
分子量574.9892 
SmileN[C@H](C(=O)OCC)CC1=CC=C(C=C1)C1=NC(=NC(=C1)O[C@@H](C(F)(F)F)C1=C(C=C(C=C1)Cl)N1N=C(C=C1)C)N
InChiKeyMDSQOJYHHZBZKA-GBXCKJPGSA-N
InChiInChI=1S/C27H26ClF3N6O3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29,30)31)19-9-8-18(28)13-22(19)37-11-10-15(2)36-37/h4-11,13-14,20,24H,3,12,32H2,1-2H3,(H2,33,34,35)/t20-,24+/m0/s1
Cas号1033805-22-9
相关CAS号

订购信息

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

17011722 - Telotristat ethyl | CAS 1033805-22-9

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