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Telatinib

Catalog No.: 121432
Cas No.: 332012-40-5
Purity : 98% 
121432 - Telatinib | CAS 332012-40-5

Catalog number : 121432

CAS number : 332012-40-5

分子式 : C20H16ClN5O3 

分子量 : 409.826 

Iupac 化学名称 : 4-[[4-(4-chloroanilino)furo[2,3-d]pyridazin-7-yl]oxymethyl]-N-methylpyridine-2-carboxamide 

Smile : CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl

InChiKey : QFCXANHHBCGMAS-UHFFFAOYSA-N

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同义词Bay 57-9352 
英文同义词Bay 57-9352 
分子式C20H16ClN5O3 
分子量409.826 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl
InChiKeyQFCXANHHBCGMAS-UHFFFAOYSA-N
InChiInChI=1S/C20H16ClN5O3/c1-22-19(27)16-10-12(6-8-23-16)11-29-20-17-15(7-9-28-17)18(25-26-20)24-14-4-2-13(21)3-5-14/h2-10H,11H2,1H3,(H,22,27)(H,24,25)
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Telatinib is a potent inhibitor of VEGFR2/3, c-Kit and PDGFR with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively. 

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