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Tariquidar

Catalog No.: 111911
Cas No.: 206873-63-4
Purity : 98% 
111911 - Tariquidar | CAS 206873-63-4

Catalog number : 111911

CAS number : 206873-63-4

分子式 : C38H38N4O6 

分子量 : 646.73 

Iupac 化学名称 : N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide 

Smile : COC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=CC=C6N=C5)OC)OC)OC

InChiKey : LGGHDPFKSSRQNS-UHFFFAOYSA-N

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同义词XR 9576; XR9576; XR-9576; D06008 
英文同义词XR 9576; XR9576; XR-9576; D06008 
分子式C38H38N4O6 
分子量646.73 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCOC1=C(C=C2CN(CCC2=C1)CCC3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4NC(=O)C5=CC6=CC=CC=C6N=C5)OC)OC)OC
InChiKeyLGGHDPFKSSRQNS-UHFFFAOYSA-N
InChiInChI=1S/C38H38N4O6/c1-45-33-18-25-14-16-42(23-28(25)19-34(33)46-2)15-13-24-9-11-29(12-10-24)40-38(44)30-20-35(47-3)36(48-4)21-32(30)41-37(43)27-17-26-7-5-6-8-31(26)39-22-27/h5-12,17-22H,13-16,23H2,1-4H3,(H,40,44)(H,41,43)
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Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. 

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