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TSU-68(SU6668,Orantinib)

Catalog No.: 51916
Cas No.: 252916-29-3
Purity : 98% 
51916 - TSU-68(SU6668,Orantinib) | CAS 252916-29-3

Catalog number : 51916

CAS number : 252916-29-3

分子式 : C18H18N2O3 

分子量 : 310.35 

Iupac 化学名称 : (Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid 

Smile : CC=1NC(=C(C1CCC(=O)O)C)\C=C\1/C(NC2=CC=CC=C12)=O

InChiKey : NHFDRBXTEDBWCZ-ZROIWOOFSA-N

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同义词TSU-68,SU6668,Orantinib 
英文同义词TSU-68,SU6668,Orantinib 
分子式C18H18N2O3 
分子量310.35 
外观solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 6 months-80ºCin solvent 
运输条件Shipped under ambient temperature 
SmileCC=1NC(=C(C1CCC(=O)O)C)\C=C\1/C(NC2=CC=CC=C12)=O
InChiKeyNHFDRBXTEDBWCZ-ZROIWOOFSA-N
InChiInChI=1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
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TSU-68 (SU6668, Orantinib) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR.

 

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