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TP0463518

Catalog No.: 1812282
Cas No.: 1558021-37-0
Purity : >98%

TP0463518是一种新型高效的HIF脯氨酰羟化酶(PHD)抑制剂。TP0463518竞争性的抑制人类PHD2的Ki值为 5.3 nM 。

For research use only. We do not sell to patients.

Chemical Information

名称TP0463518
Iupac 化学名称(1-((6-(4-chlorophenoxy)pyridin-3-yl)methyl)-4-hydroxy-2-oxo-1,2,5,6-tetrahydropyridine-3-carbonyl)glycine
同义词TP0463518; TP-0463518; TP 0463518;
英文同义词TP0463518; TP-0463518; TP 0463518;
分子式C20H18ClN3O6
分子量431.829
SmileO=C(O)CNC(C1=C(O)CCN(CC2=CC=C(OC3=CC=C(Cl)C=C3)N=C2)C1=O)=O
InChiKeyHMMHKGLPKAQOOH-UHFFFAOYSA-N
InChiInChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)
Cas号1558021-37-0
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Ordering Information

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Formulation类白色至白色固体
纯度>98%
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

1812282 - TP0463518  | CAS 1558021-37-0

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