SB1317 (TG02) is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. SB1317 was soluble, highly permeable in Caco-2 cells, and showed > 99% binding to plasma from mice, dog and humans.
仅供研究使用。 我们不向患者出售。
| 名称 | TG02 ( SB1317 ) |
|---|---|
| Iupac 化学名称 | 14-Methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene |
| 同义词 | TG-02 ; TG 02 ; TG02 ; SB1317; SB-1317 ; SB 1317 |
| 英文同义词 | TG-02 ; TG 02 ; TG02 ; SB1317; SB-1317 ; SB 1317 |
| 分子式 | C23H24N4O |
| 分子量 | 372.46 |
| Smile | CN1CC=2C=CC=C(NC=3N=CC=C(C=4C=CC=C(OCCC=CC1)C4)N3)C2 |
| InChiKey | VXBAJLGYBMTJCY-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26) |
| Cas号 | 937270-47-8 |
| 相关CAS号 | 937270-47-8 |
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | 类白色至白色固体 |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | 短期可在0-4度保存,数天至数月;长期可在-20度保存三年。 |
| 可溶性 | Soluble in DMSO |
| 处理方式 | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 |
| Targets | CDK/JAK2/FLT3 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |