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TG003

Catalog No.: 110226
Cas No.: 300801-52-9
Purity : 98% 
110226 - TG003 | CAS 300801-52-9

Catalog number : 110226

CAS number : 300801-52-9

分子式 : C12H15NO2S 

分子量 : 237.318 

Iupac 化学名称 : (1Z)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one 

Smile : CCN1C2=C(C=CC(=C2)OC)SC1=CC(=O)C

InChiKey : BGVLELSCIHASRV-UHFFFAOYSA-N

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同义词TG 003; TG-003; Clk Inhibitor, TG003; Cdc2-Like Kinase Inhibitor 
英文同义词TG 003; TG-003; Clk Inhibitor, TG003; Cdc2-Like Kinase Inhibitor 
分子式C12H15NO2S 
分子量237.318 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCCN1C2=C(C=CC(=C2)OC)SC1=CC(=O)C
InChiKeyBGVLELSCIHASRV-UHFFFAOYSA-N
InChiInChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3
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TG003 is a novel benzothiazole compound that demonstrates potent inhibition of Clk1/Sty and Clk4 with IC50 values of 20 and 15 nM, respectively, which exhibits considerably weaker inhibition of Clk2 and Clk3 (IC50 = 200 nM and >10 M, respectively). 

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