TD-106 is a cereblon (CRBN) modulator, which can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation.
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化学信息
| 名称 | TD-106 |
| 同义词 | TD-106;TD106;TD 106. |
| 英文同义词 | TD-106;TD106;TD 106. |
| 分子式 | C12H11N5O3 |
| 分子量 | 273.25 |
| Smile | NC1=CC=CC(N=NN2C3CCC(NC3=O)=O)=C1C2=O |
| InChiKey | |
| InChi | |
| Cas号 | 2250288-69-6 |
| 相关CAS号 | |
| 外观性状 | Off-white solid to white solid |
| 纯度 | >98% |
| 存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |