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TAK-733

Catalog No.: 010813
Cas No.: 1035555-63-5
Purity : 98% 
010813 - TAK-733 | CAS 1035555-63-5

Catalog number : 010813

CAS number : 1035555-63-5

分子式 : C17H15F2IN4O4 

分子量 : 504.227 

Iupac 化学名称 : 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-(2-fluoro-4-iodoanilino)-8-methylpyrido[2,3-d]pyrimidine-4,7-dione 

Smile : CN1C2=C(C(=C(C1=O)F)NC3=C(C=C(C=C3)I)F)C(=O)N(C=N2)CC(CO)O

InChiKey : RCLQNICOARASSR-UHFFFAOYSA-N

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同义词TAK733; TAK 733 
英文同义词TAK733; TAK 733 
分子式C17H15F2IN4O4 
分子量504.227 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCN1C2=C(C(=C(C1=O)F)NC3=C(C=C(C=C3)I)F)C(=O)N(C=N2)CC(CO)O
InChiKeyRCLQNICOARASSR-UHFFFAOYSA-N
InChiInChI=1S/C17H15F2IN4O4/c1-23-15-12(16(27)24(7-21-15)5-9(26)6-25)14(13(19)17(23)28)22-11-3-2-8(20)4-10(11)18/h2-4,7,9,22,25-26H,5-6H2,1H3
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TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. 

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