武汉永璨生物科技有限公司
+86-17702719238 sales@sun-shinechem.com

Sobetirome

编号: 16070907
Cas号: 211110-63-3
纯度: 98% by HPLC 

Sobetirome, also known as GC-1 and QRX-431, is a hyroid hormone beta-receptor agonist. Sobetirome inhibits proliferation but induces differentiation and TR beta mRNA expression in mouse and rat osteoblast-like cells. Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol through activation of liver TRbeta without stimulating cardiac function through TRalpha activation in the heart. The tissue selective thyromimetic properties of sobetirome have been demonstrated in numerous animal models, which led to its clinical development as a novel cholesterol-lowering agent. 

仅供研究使用。 我们不向患者出售。

化学信息

名称Sobetirome
Iupac 化学名称2-(4-(4-hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid 
同义词GC-1; GC1; GC 1; QRX-431 
英文同义词GC-1; GC1; GC 1; QRX-431 
分子式C20H24O4 
分子量328.408 
SmileOC1=C(C=C(CC2=C(C=C(OCC(=O)O)C=C2C)C)C=C1)C(C)C
InChiKeyQNAZTOHXCZPOSA-UHFFFAOYSA-N
InChiInChI=1S/C20H24O4/c1-12(2)17-9-15(5-6-19(17)21)10-18-13(3)7-16(8-14(18)4)24-11-20(22)23/h5-9,12,21H,10-11H2,1-4H3,(H,22,23)
Cas号211110-63-3
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
Request Bulk Quote Download MSDS 电话 : +86-177 0271 9238   Email : sales@sun-shinechem.com
外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16070907 - Sobetirome | CAS 211110-63-3

快速订购

Change