Siponimod
Catalog No: 16071404
CAS Number: 1230487-00-9
Purity: 98%
Siponimod, also known as BAF-312, is a a potent and orally selective S1P Receptor Modulator with EC50 value of 0.39nM for S1P1 receptors and 0.98nM for S1P5 receptors, respectively. Development of sphingosine-1-phosphate receptor 1 (S1P1) modulators to dampen inflammation and its sequelae is becoming increasingly promising for treating medical conditions characterized by significant immunopathology.
仅供研究使用。 我们不向患者出售。
Chemical Information
| Name | Siponimod |
|---|---|
| Iupac Chemical Name | (E)-1-(4-(1-(((4-cyclohexyl-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic acid |
| Synonyms | BAF-312; BAF 312; BAF312; Siponimod |
| 英文同义词 | BAF-312; BAF 312; BAF312; Siponimod |
| Molecular Formula | C29H35F3N2O3 |
| Molecular Weight | 516.6 |
| Smile | C1(CCCCC1)C1=C(C=C(CO\N=C(/C)\C2=CC(=C(CN3CC(C3)C(=O)O)C=C2)CC)C=C1)C(F)(F)F |
| InChiKey | KIHYPELVXPAIDH-HNSNBQBZSA-N |
| InChi | InChI=1S/C29H35F3N2O3/c1-3-21-14-23(10-11-24(21)15-34-16-25(17-34)28(35)36)19(2)33-37-18-20-9-12-26(22-7-5-4-6-8-22)27(13-20)29(30,31)32/h9-14,22,25H,3-8,15-18H2,1-2H3,(H,35,36)/b33-19+ |
| CAS Number | 1230487-00-9 |
| 相关CAS号 |
Ordering Information
| 包装 | Price | 库存 | Purity | 备货期 |
|---|---|---|---|---|
| 大货 | Enquiry | Enquiry | Enquiry |
| 外观性状 | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| 处理方式 | |
| Shipping Condition | Shipped under ambient temperature |
| 海关编码 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
