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Semaxanib (SU5416)

Catalog No.: 51803
Cas No.: 204005-46-9
Purity : 98% 
51803 - Semaxanib (SU5416) | CAS 204005-46-9

Catalog number : 51803

CAS number : 204005-46-9

分子式 : C15H14N2O 

分子量 : 238.28 

Iupac 化学名称 : 2H-Indol-2-one,3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-, (3Z)- 

Smile : Cc1cc([nH]c1/C=C\2/c3ccccc3NC2=O)C

InChiKey : WUWDLXZGHZSWQZ-WQLSENKSSA-N

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同义词Semaxanib;SU5416 
英文同义词Semaxanib;SU5416 
分子式C15H14N2O 
分子量238.28 
外观yellow solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileCc1cc([nH]c1/C=C\2/c3ccccc3NC2=O)C
InChiKeyWUWDLXZGHZSWQZ-WQLSENKSSA-N
InChiInChI=1S/C15H14N2O/c1-9-7-10(2)16-14(9)8-12-11-5-3-4-6-13(11)17-15(12)18/h3-8,16H,1-2H3,(H,17,18)/b12-8-
MDLMFCD09763655
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Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 M, 20-fold more selective for VEGFR than PDGFR, lack of activity against EGFR, InsR and FGFR. Phase 3. 

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