Saruparib
编号: 24100
Cas号: 2589531-76-8
纯度: 98% Min.
Saruparib, also known as AZD5305 is a potent, selective and oral active PARP inhibitor. AZD5305 is a highly potent inhibitor of PARP1, with significant PARP1-DNA trapping activity, no PARP2-activity, nor binding activity to any other members of the PARP family. AZD5305 has excellent secondary pharmacology and physicochemical properties as well as high oral bioavailability in preclinical species.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Saruparib |
|---|---|
| Iupac 化学名称 | 5-(4-((7-ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)-N-methylpicolinamide |
| 同义词 | AZD5305; AZD-5305; AZD 5305; Saruparib |
| 英文同义词 | AZD5305; AZD-5305; AZD 5305; Saruparib |
| 分子式 | C22H26N6O2 |
| 分子量 | 406.48 |
| Smile | O=C(C1=NC=C(N2CCN(CC3=CC(N4)=C(N=C3)C=C(CC)C4=O)CC2)C=C1)NC |
| InChiKey | WQAVGRAETZEADU-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H26N6O2/c1-3-16-11-19-20(26-21(16)29)10-15(12-24-19)14-27-6-8-28(9-7-27)17-4-5-18(25-13-17)22(30)23-2/h4-5,10-13H,3,6-9,14H2,1-2H3,(H,23,30)(H,26,29) |
| Cas号 | 2589531-76-8 |
| 相关CAS号 |
订购信息
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