Sacubitril sodium
编号: 17030108
Cas号: 149690-05-1
纯度: 98%
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
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化学信息
| 名称 | Sacubitril sodium |
|---|---|
| Iupac 化学名称 | Sacubitril sodium |
| 同义词 | Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696 |
| 英文同义词 | Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696 |
| 分子式 | C24H28NNaO5 |
| 分子量 | 433.4798 |
| InChiKey | |
| InChi | |
| Cas号 | 149690-05-1 |
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订购信息
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