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SU11274

Catalog No.: 122912
Cas No.: 658084-23-2
Purity : 98% 
122912 - SU11274 | CAS 658084-23-2

Catalog number : 122912

CAS number : 658084-23-2

分子式 : C28H30ClN5O4S 

分子量 : 568.087 

Iupac 化学名称 : (3Z)-N-(3-chlorophenyl)-3-[[3,5-dimethyl-4-(4-methylpiperazine-1-carbonyl)-1H-pyrrol-2-yl]methylidene]-N-methyl-2-oxo-1H-indole-5-sulfonamide 

Smile : CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O

InChiKey : FPYJSJDOHRDAMT-UHFFFAOYSA-N

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同义词SU 11274; PKI-SU11274; SU-11274 
英文同义词SU 11274; PKI-SU11274; SU-11274 
分子式C28H30ClN5O4S 
分子量568.087 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O
InChiKeyFPYJSJDOHRDAMT-UHFFFAOYSA-N
InChiInChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35)
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SU11274 is a selective Met inhibitor with IC50 of 10 nM, no effects on PGDFR, EGFR or Tie2. 

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