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SNS-314 Mesylate

Catalog No.: 52102
Cas No.: 1057249-41-8
Purity : 98% 
52102 - SNS-314 Mesylate | CAS 1057249-41-8

Catalog number : 52102

CAS number : 1057249-41-8

分子式 : C18H15ClN6OS2.CH4O3S 

分子量 : 527.04 

Iupac 化学名称 : 1-(3-chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea methanesulfonate 

Smile : CS(=O)(=O)O.ClC=1C=C(C=CC1)NC(=O)NC=1SC(=CN1)CCNC=1C2=C(N=CN1)C=CS2

InChiKey : FYCODPVDEFFWSR-UHFFFAOYSA-N

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同义词N/A 
英文同义词N/A 
分子式C18H15ClN6OS2.CH4O3S 
分子量527.04 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileCS(=O)(=O)O.ClC=1C=C(C=CC1)NC(=O)NC=1SC(=CN1)CCNC=1C2=C(N=CN1)C=CS2
InChiKeyFYCODPVDEFFWSR-UHFFFAOYSA-N
InChiInChI=1S/C18H15ClN6OS2.CH4O3S/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16;1-5(2,3)4/h1-3,5,7-10H,4,6H2,(H,20,22,23)(H2,21,24,25,26);1H3,(H,2,3,4)
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SNS-314 Mesylate is a potent and selective inhibitor of Aurora AAurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1. 

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