SH-4-54
编号: 16071406
Cas号: 1456632-40-8
纯度: 98% by HPLC
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5, respectively. SH-4-54 potently kills glioblastoma brain cancer stem cells (BTSCs) and effectively suppresses STAT3 phosphorylation and its downstream transcriptional targets at low nM concentrations. Moreover, in vivo,SH-4-54 exhibited blood-brain barrier permeability, potently controlled glioma tumor growth, and inhibited pSTAT3 in vivo.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | SH-4-54 |
|---|---|
| Iupac 化学名称 | 4-(N-(4-cyclohexylbenzyl)-2-((2,3,4,5,6-pentafluoro-N-methylphenyl)sulfonamido)acetamido)benzoic acid |
| 同义词 | SH-4-54; SH 4-54; |
| 英文同义词 | SH-4-54; SH 4-54; |
| 分子式 | C29H27F5N2O5S |
| 分子量 | 610.596 |
| InChiKey | |
| InChi | |
| Cas号 | 1456632-40-8 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
