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SGI-1776

Catalog No.: 122945
Cas No.: 1025065-69-3
Purity : 98% 
122945 - SGI-1776 | CAS 1025065-69-3

Catalog number : 122945

CAS number : 1025065-69-3

分子式 : C20H22F3N5O 

分子量 : 405.417 

Iupac 化学名称 : N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine 

Smile : CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2

InChiKey : MHXGEROHKGDZGO-UHFFFAOYSA-N

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同义词SGI 1776; SGI1776 
英文同义词SGI 1776; SGI1776 
分子式C20H22F3N5O 
分子量405.417 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2
InChiKeyMHXGEROHKGDZGO-UHFFFAOYSA-N
InChiInChI=1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)
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SGI-1776 is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM; 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin.
 

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