SEA0400 is a Na+/Ca2+ exchanger 1 inhibitor. SEA0400 prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. SEA0400 reduces calcium overload induced by ischemia and reperfusion in mouse ventricular myocytes. SEA0400 attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia. SEA0400, preserves cardiac function and high-energy phosphates against ischemia/reperfusion injury.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | SEA0400 |
| Iupac 化学名称 | 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline |
| 同义词 | C21H19F2NO3 |
| 英文同义词 | C21H19F2NO3 |
| 分子式 | C21H19F2NO3 |
| 分子量 | 371.3838 |
| Smile | FC1=C(C=C(C=C1)F)COC1=CC=C(OC2=C(N)C=C(C=C2)OCC)C=C1 |
| InChiKey | YSUBLPUJDOWYDP-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H19F2NO3/c1-2-25-18-8-10-21(20(24)12-18)27-17-6-4-16(5-7-17)26-13-14-11-15(22)3-9-19(14)23/h3-12H,2,13,24H2,1H3 |
| Cas号 | 223104-29-8 |
| 相关CAS号 | |
| 外观性状 | Solid powder |
| 纯度 | 98% by HPLC |
| 存储 | -20 ºC for 3 years |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |