SCH-58261
编号: 16060802
Cas号: 160098-96-4
纯度: 98% by HPLC
SCH-58261 is a potent and selective adenosine A(2A) receptor antagonist. SCH-58261 is a useful ligand in autoradiographic studies. Blockade of adenosine A2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats. SCH 58261 counteracts parkinsonian-like muscle rigidity in rats. SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat. SCH 58261 protects from neurological deficit, brain damage and activation of p38 MAPK in rat focal cerebral ischemia
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | SCH-58261 |
|---|---|
| Iupac 化学名称 | 2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine |
| 同义词 | SCH-58261; SCH 58261; SCH58261 |
| 英文同义词 | SCH-58261; SCH 58261; SCH58261 |
| 分子式 | C18H15N7O |
| 分子量 | 345.366 |
| Smile | O1C(=CC=C1)C1=NN2C(=NC3=C(C2=N1)C=NN3CCC3=CC=CC=C3)N |
| InChiKey | UTLPKQYUXOEJIL-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H15N7O/c19-18-22-16-13(11-20-24(16)9-8-12-5-2-1-3-6-12)17-21-15(23-25(17)18)14-7-4-10-26-14/h1-7,10-11H,8-9H2,(H2,19,22) |
| Cas号 | 160098-96-4 |
| 相关CAS号 |
订购信息
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