SB-742457(Intepirdine) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63; exhibits >100-fold selectivity over other receptors.
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| 名称 | SB-742457 ( Intepirdine ) |
|---|---|
| Iupac 化学名称 | 3-(benzenesulfonyl)-8-piperazin-1-ylquinoline |
| 同义词 | GSK-742457 ; RVT-101 ; Intepirdine ; SB-742457 ; SB742457 |
| 英文同义词 | GSK-742457 ; RVT-101 ; Intepirdine ; SB-742457 ; SB742457 |
| 分子式 | C19H19N3O2S |
| 分子量 | 353.438 |
| Smile | C1CN(CCN1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC=C4 |
| InChiKey | JJZFWROHYSMCMU-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2 |
| Cas号 | 607742-69-8 |
| 相关CAS号 | 607742-69-8 |
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Light-yellow solid |
|---|---|
| 纯度 | 98% |
| 存储 | -20 ºC for 3 years |
| 可溶性 | Soluble in DMSO |
| 处理方式 | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 |
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |