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SB 525334

Catalog No.: 102205
Cas No.: 356559-20-1
Purity : 98% 
102205 - SB 525334 | CAS 356559-20-1

Catalog number : 102205

CAS number : 356559-20-1

分子式 : C21H21N5 

分子量 : 343.42 

Iupac 化学名称 : 6-[2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline 

Smile : C(C)(C)(C)C=1NC(=C(N1)C=1C=C2N=CC=NC2=CC1)C1=NC(=CC=C1)C

InChiKey : DKPQHFZUICCZHF-UHFFFAOYSA-N

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同义词SB-525334; SB525334 
英文同义词SB-525334; SB525334 
分子式C21H21N5 
分子量343.42 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileC(C)(C)(C)C=1NC(=C(N1)C=1C=C2N=CC=NC2=CC1)C1=NC(=CC=C1)C
InChiKeyDKPQHFZUICCZHF-UHFFFAOYSA-N
InChiInChI=1S/C21H21N5/c1-13-6-5-7-16(24-13)19-18(25-20(26-19)21(2,3)4)14-8-9-15-17(12-14)23-11-10-22-15/h5-12H,1-4H3,(H,25,26)
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SB 525334 is a potent and selective inhibitor of TGF_beta_ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6. 

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