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S49076

编号: 17021309
Cas号: 1265965-22-7
纯度: 98% 

S49076 is a novel, potent inhibitor of METAXL/MER, and FGFR1/2/3 with IC50 values below 20 nmol/L.

S49076 potently blocks cellular phosphorylation of MET, AXL, and FGFRs and inhibits downstream signaling in vitro and in vivo. In cell models, S49076 inhibits the proliferation of MET- and FGFR2-dependent gastric cancer cells, blocks MET-driven migration of lung carcinoma cells, and inhibits colony formation of hepatocarcinoma cells expressing FGFR1/2 and AXL. S49076 inhibits viability, motility, and three-dimensional colony formation of cancer cells expressing MET, AXL, or FGFRs.

 

仅供研究使用。 我们不向患者出售。

化学信息

名称S49076
Iupac 化学名称S49076 
同义词N/A 
英文同义词N/A 
分子式C22H22N4O4S 
分子量438.50 
InChiKey
InChi
Cas号1265965-22-7
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
Request Bulk Quote Download MSDS 电话 : +86-177 0271 9238   Email : sales@sun-shinechem.com
外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

17021309 - S49076 | CAS 1265965-22-7

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