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Rilpivirine

Catalog No.: 111904
Cas No.: 500287-72-9
Purity : 98% 
111904 - Rilpivirine | CAS 500287-72-9

Catalog number : 111904

CAS number : 500287-72-9

分子式 : C22H18N6 

分子量 : 366.419 

Iupac 化学名称 : 4-[[4-[4-[(E)-2-cyanoethenyl]-2,6-dimethylanilino]pyrimidin-2-yl]amino]benzonitrile 

Smile : CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)C=CC#N

InChiKey : YIBOMRUWOWDFLG-UHFFFAOYSA-N

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同义词TMC278; TMC-278; TMC 278; Edurant 
英文同义词TMC278; TMC-278; TMC 278; Edurant 
分子式C22H18N6 
分子量366.419 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)C=CC#N
InChiKeyYIBOMRUWOWDFLG-UHFFFAOYSA-N
InChiInChI=1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)
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Rilpivirine is a pharmaceutical drug, developed by Tibotec, for the treatment of HIV infection. It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. 

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