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Rigosertib (ON-01910)

Catalog No.: 52010
Cas No.: 1225497-78-8
Purity : 98% 
52010 - Rigosertib (ON-01910) | CAS 1225497-78-8

Catalog number : 52010

CAS number : 1225497-78-8

分子式 : C21H24NNaO8S 

分子量 : 473.47 

Iupac 化学名称 : sodium (E)-2-((2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)amino)acetate

Smile : COc1ccc(cc1NCC(=O)[O-])CS(=O)(=O)/C=C/c2c(cc(cc2OC)OC)OC.[Na+]

InChiKey : VLQLUZFVFXYXQE-USRGLUTNSA-M

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同义词Rigosertib,ON-01910 
英文同义词Rigosertib,ON-01910 
分子式C21H24NNaO8S 
分子量473.47 
外观off-white solid 
纯度98% 
可溶性50mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileCOc1ccc(cc1NCC(=O)[O-])CS(=O)(=O)/C=C/c2c(cc(cc2OC)OC)OC.[Na+]
InChiKeyVLQLUZFVFXYXQE-USRGLUTNSA-M
InChiInChI=1S/C21H25NO8S.Na/c1-27-15-10-19(29-3)16(20(11-15)30-4)7-8-31(25,26)13-14-5-6-18(28-2)17(9-14)22-12-21(23)24;/h5-11,22H,12-13H2,1-4H3,(H,23,24);/q;+1/p-1/b8-7+;
MDLMFCD11655911
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Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Phase 3. 

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