Recilisib, also known as ON 01210.Na, is a radioprotectant, which modifys cell cycle distribution patterns in cancer cells subjected to radiation therapy, and it has been identified as a potential candidate for radiation protection studies. It appears that Recilisib radioprotective mechanisms involve prevention of p53-dependent and independent radiation-induced apoptosis.
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化学信息
名称 | Recilisib sodium |
Iupac 化学名称 | Recilisib sodium |
同义词 | Recilisib; ON 01210.Na; ON-01210; ON01210; ON01210 |
英文同义词 | Recilisib; ON 01210.Na; ON-01210; ON01210; ON01210 |
分子式 | C16H12ClNaO4S |
分子量 | 358.7678 |
Smile | c1cc(ccc1CS(=O)(=O)/C=C/c2ccc(cc2)C(=O)O)Cl |
InChiKey | KBEKQQJUNVQLDZ-MDZDMXLPSA-N |
InChi | InChI=1S/C16H13ClO4S/c17-15-7-3-13(4-8-15)11-22(20,21)10-9-12-1-5-14(6-2-12)16(18)19/h1-10H,11H2,(H,18,19)/b10-9+ |
Cas号 | 334969-03-8 |
MDL | MFCD07366276 |
相关CAS号 | |
外观性状 | off-white solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |