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RWJ-56110

Catalog No.: 19353
Cas No.: 252889-88-6
Purity : >98%
19353 - RWJ-56110 | CAS 252889-88-6

Catalog number : 19353

CAS number : 252889-88-6

分子式 : C41H43Cl2F2N7O3

分子量 : 790.74

Iupac 化学名称 : (2S)-4-amino-2-[[(2S)-2-[[1-[(2,6-dichlorophenyl)methyl]-3-(pyrrolidin-1-ylmethyl)indol-6-yl]carbamoylamino]-3-(3,4-difluorophenyl)propanoyl]amino]-N-(phenylmethyl)butanamide

Smile : O=C(NCC1=CC=CC=C1)[C@@H](NC([C@@H](NC(NC2=CC3=C(C=C2)C(CN4CCCC4)=CN3CC5=C(Cl)C=CC=C5Cl)=O)CC6=CC=C(F)C(F)=C6)=O)CCN

InChiKey : SWPAWRHBFNDXEU-BCRBLDSWSA-N

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同义词RWJ-56110; RWJ 56110; RWJ56110.
英文同义词RWJ-56110; RWJ 56110; RWJ56110.
分子式C41H43Cl2F2N7O3
分子量790.74
外观类白色至白色固体
纯度>98%
可溶性可溶于DMSO
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileO=C(NCC1=CC=CC=C1)[C@@H](NC([C@@H](NC(NC2=CC3=C(C=C2)C(CN4CCCC4)=CN3CC5=C(Cl)C=CC=C5Cl)=O)CC6=CC=C(F)C(F)=C6)=O)CCN
InChiKeySWPAWRHBFNDXEU-BCRBLDSWSA-N
InChiInChI=1S/C41H43Cl2F2N7O3/c42-32-9-6-10-33(43)31(32)25-52-24-28(23-51-17-4-5-18-51)30-13-12-29(21-38(30)52)48-41(55)50-37(20-27-11-14-34(44)35(45)19-27)40(54)49-36(15-16-46)39(53)47-22-26-7-2-1-3-8-26/h1-3,6-14,19,21,24,36-37H,4-5,15-18,20,22-23,25,46H2,(H,47,53)(H,49,54)(H2,48,50,55)/t36-,37-/m0/s1
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RWJ-56110是一种选择性蛋白酶活化受体-1 (PAR1)拮抗剂。它阻断凝血酶诱导的血小板聚集和HUVECs中MAPK的激活。

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