RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.
RU-SKI 43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.
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| 名称 | RU-SKI 43 |
|---|---|
| Iupac 化学名称 | RU-SKI 43 |
| 同义词 | RU-SKI43; Hhat Inhibitor |
| 英文同义词 | RU-SKI43; Hhat Inhibitor |
| 分子式 | C22H30N2O2S |
| 分子量 | 386.55 |
| InChiKey | |
| InChi | |
| Cas号 | 1043797-53-0 |
| 相关CAS号 |
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| 大货 | 询价 | 询价 | 询价 |