RPI-1
编号: 17030301
Cas号: 269730-03-2
纯度: 98%
RPI-1 is an ATP-dependent RET kinase inhibitor. Oral treatment with RPI-1 caused growth arrest or regression in 81% treated tumors. Following treatment suspension, tumor inhibition was maintained (51%, P<0.05, 100 days) and cures were achieved in 2/11 mice. In vivo effects of RPI-1 were reflected in activation of BAD, cleavage of caspases, apoptotic DNA fragmentation and inhibition of VEGF production observed in in vitro RPI-1-treated TT cells.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | RPI-1 |
|---|---|
| Iupac 化学名称 | 1,3-dihydro-3-[(4-hydroxyphenyl)methylene]-5,6-dimethoxy-2H-indol-2-one |
| 同义词 | RPI-1; RPI1; RPI 1 |
| 英文同义词 | RPI-1; RPI1; RPI 1 |
| 分子式 | C17H15NO4 |
| 分子量 | 297.31 |
| Smile | OC1=CC=C(C=C1)C=C1C(NC2=CC(=C(C=C12)OC)OC)=O |
| InChiKey | JGSMCYNBVCGIHC-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H15NO4/c1-21-15-8-12-13(7-10-3-5-11(19)6-4-10)17(20)18-14(12)9-16(15)22-2/h3-9,19H,1-2H3,(H,18,20) |
| Cas号 | 269730-03-2 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
