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R406 free base

Catalog No.: 122927
Cas No.: 841290-80-0
Purity : 98% 
122927 - R406 free base | CAS 841290-80-0

Catalog number : 122927

CAS number : 841290-80-0

分子式 : C22H23FN6O5 

分子量 : 470.454 

Iupac 化学名称 : 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one 

Smile : CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C

InChiKey : NHHQJBCNYHBUSI-UHFFFAOYSA-N

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同义词R-406; R406 
英文同义词R-406; R406 
分子式C22H23FN6O5 
分子量470.454 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
InChiKeyNHHQJBCNYHBUSI-UHFFFAOYSA-N
InChiInChI=1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,28,29,30)
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R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of Fc receptor signaling (EC(50) for degranulation = 56-64 nM).
 

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