Pemigatinib (INCB054828)
编号: 1810164
Cas号: 1513857-77-6
纯度: 98%
Pemigatinib (INCB054828) is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Pemigatinib (INCB054828) |
|---|---|
| Iupac 化学名称 | 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-[(morpholin-4-yl)methyl]-1,3,4,7-tetrahydro-2Hpyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one |
| 同义词 | Pemigatinib; INCB054828 |
| 英文同义词 | Pemigatinib; INCB054828 |
| 分子式 | C24H27F2N5O4 |
| 分子量 | 487.5 |
| Smile | O=C1N(CC)C2=C3C(NC(CN4CCOCC4)=C3)=NC=C2CN1C5=C(F)C(OC)=CC(OC)=C5F |
| InChiKey | HCDMJFOHIXMBOV-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H27F2N5O4/c1-4-30-21-14(11-27-23-16(21)9-15(28-23)13-29-5-7-35-8-6-29)12-31(24(30)32)22-19(25)17(33-2)10-18(34-3)20(22)26/h9-11H,4-8,12-13H2,1-3H3,(H,27,28) |
| Cas号 | 1513857-77-6 |
| 相关CAS号 | 1513857-77-6 (free base) 1513857-77-6 (HCl) |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Off-white solid to white solid |
|---|---|
| 纯度 | 98% |
| 存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| 可溶性 | Soluble in DMSO |
| 处理方式 | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| 运输条件 | Shipped under ambient temperature |
| 海关编码 | 2933599090 |
| Targets | FGFR inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
