Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.ASP015K suppresses the IL-2-induced proliferation of human T cells with greater potency than EPO-induced proliferation of human erythroleukemia cells. In human whole blood, ASP015K inhibits STAT5 phosphorylation (pSTAT5).
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Peficitinib (ASP015K, JNJ-54781532) |
| Iupac 化学名称 | Peficitinib (ASP015K, JNJ-54781532) |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C18H22N4O2 |
| 分子量 | 326.3 |
| InChiKey | |
| InChi | |
| Cas号 | 944118-01-8 |
| 相关CAS号 | |
| 外观性状 | crystalline solid |
| 纯度 | 98% |
| 存储 | 3 years -20ºCpowder |
| 可溶性 | Soluble in DMSO |
| 处理方式 | |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |