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PH-797804

Catalog No.: 17030914
Cas No.: 586379-66-0
Purity : 98% 
17030914 - PH-797804 | CAS 586379-66-0

Catalog number : 17030914

CAS number : 586379-66-0

分子式 : C22H19BrF2N2O3 

分子量 : 477.29867 

Iupac 化学名称 : 3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide 

Smile : FC1=C(COC2=C(C(N(C(=C2)C)C=2C=C(C(=O)NC)C=CC2C)=O)Br)C=CC(=C1)F

InChiKey : KCAJXIDMCNPGHZ-UHFFFAOYSA-N

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同义词PH-797804; PH 797804; PH797804 
英文同义词PH-797804; PH 797804; PH797804 
分子式C22H19BrF2N2O3 
分子量477.29867 
外观类白色至白色固体
纯度98% 
可溶性可溶于DMSO
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileFC1=C(COC2=C(C(N(C(=C2)C)C=2C=C(C(=O)NC)C=CC2C)=O)Br)C=CC(=C1)F
InChiKeyKCAJXIDMCNPGHZ-UHFFFAOYSA-N
InChiInChI=1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)
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PH-797804是一种有效的p38 mit原活化蛋白(MAP)激酶的选择性抑制剂。PH-797804降低了3个PDXs的肿瘤生长,这与结肠肿瘤细胞增殖和存活有关。

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