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PF-543 Citrate

Catalog No.: 6111525
Cas No.: 1415562-83-2
Purity : 98% 

PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.


PF-543 is the most potent inhibitor of SphK1 described to date and it will be useful for dissecting specific roles of SphK1-driven S1P signalling.



 

For research use only. We do not sell to patients.

Chemical Information

名称PF-543 Citrate
Iupac 化学名称PF-543 Citrate 
同义词PF543 Citrate; PF 543 Citrate 
英文同义词PF543 Citrate; PF 543 Citrate 
分子式C33H39NO11S 
分子量657.73 
SmileCc1cc(cc(c1)OCc2ccc(cc2)CN3CCC[C@@H]3CO)CS(=O)(=O)c4ccccc4.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
InChiKeyPWXXWUWKNPXSGW-VQIWEWKSSA-N
InChiInChI=1S/C27H31NO4S.C6H8O7/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-4,7-12,14-16,25,29H,5-6,13,17-20H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t25-;/m1./s1
Cas号1415562-83-2
MDLMFCD23098795
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

6111525 - PF-543 Citrate | CAS 1415562-83-2

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