+86-27-65522453 sales@sun-shinechem.com

PF-543 Citrate

Catalog No.: 6111525
Cas No.: 1415562-83-2
Purity : 98% 
6111525 - PF-543 Citrate | CAS 1415562-83-2

Catalog number : 6111525

CAS number : 1415562-83-2

分子式 : C33H39NO11S 

分子量 : 657.73 

Iupac 化学名称 : PF-543 Citrate 

Smile : Cc1cc(cc(c1)OCc2ccc(cc2)CN3CCC[C@@H]3CO)CS(=O)(=O)c4ccccc4.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

InChiKey : PWXXWUWKNPXSGW-VQIWEWKSSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDS电话:+86-27-65522453 | Email:sales@sun-shinechem.com
同义词PF543 Citrate; PF 543 Citrate 
英文同义词PF543 Citrate; PF 543 Citrate 
分子式C33H39NO11S 
分子量657.73 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
SmileCc1cc(cc(c1)OCc2ccc(cc2)CN3CCC[C@@H]3CO)CS(=O)(=O)c4ccccc4.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
InChiKeyPWXXWUWKNPXSGW-VQIWEWKSSA-N
InChiInChI=1S/C27H31NO4S.C6H8O7/c1-21-14-24(20-33(30,31)27-7-3-2-4-8-27)16-26(15-21)32-19-23-11-9-22(10-12-23)17-28-13-5-6-25(28)18-29;7-3(8)1-6(13,5(11)12)2-4(9)10/h2-4,7-12,14-16,25,29H,5-6,13,17-20H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t25-;/m1./s1
MDLMFCD23098795
Coming soon.

PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.


PF-543 is the most potent inhibitor of SphK1 described to date and it will be useful for dissecting specific roles of SphK1-driven S1P signalling.



 

1415562-83-2 - Request Bulk Quote

×
1415562-83-2 - Request Bulk Quote
Change