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PCI-27483

Catalog No.: 110401
Cas No.: 871266-63-6
Purity : 98% 
110401 - PCI-27483 | CAS 871266-63-6

Catalog number : 110401

CAS number : 871266-63-6

分子式 : C26H24N6O9S 

分子量 : 596.569 

Iupac 化学名称 : (S)-2-(2-(5-(5-carbamimidoyl-1H-benzo[d]imidazol-2-yl)-2',6-dihydroxy-5'-sulfamoyl-[1,1'-biphenyl]-3-yl)acetamido)succinic acid 

Smile : C1=CC2=C(C=C1C(=N)N)NC(=C3C=C(C=C(C3=O)C4=C(C=CC(=C4)S(=O)(=O)N)O)CC(=O)NC(CC(=O)O)C(=O)O)N2

InChiKey : PVTVTDSZGJFYRP-UHFFFAOYSA-N

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同义词PCI27483; PCI 27483 
英文同义词PCI27483; PCI 27483 
分子式C26H24N6O9S 
分子量596.569 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileC1=CC2=C(C=C1C(=N)N)NC(=C3C=C(C=C(C3=O)C4=C(C=CC(=C4)S(=O)(=O)N)O)CC(=O)NC(CC(=O)O)C(=O)O)N2
InChiKeyPVTVTDSZGJFYRP-UHFFFAOYSA-N
InChiInChI=1S/C26H24N6O9S/c27-24(28)12-1-3-17-18(8-12)32-25(31-17)16-6-11(7-21(34)30-19(26(38)39)10-22(35)36)5-15(23(16)37)14-9-13(42(29,40)41)2-4-20(14)33/h1-6,8-9,19,31-33H,7,10H2,(H3,27,28)(H,30,34)(H,35,36)(H,38,39)(H2,29,40,41)
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PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VIIa) with potential antineoplastic and antithrombotic activities. FVII, a serine protease, becomes activated (FVIIa) upon binding with TF forming the FVIIa/TF complex, which induces intracellular signaling pathways by activating protease activated receptor 2. 

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