Oxolinic acid
编号: 16122720
Cas号: 14698-29-4
纯度: 98%
Oxolinic acid is a quinolone antibiotic, inhibiting the enzyme DNA gyrase and DNA synthesis.It also acts as a dopamine reuptake inhibitor.Oxolinic acid, a quinolone antibacterial agent, inhibits reversibly the ATP-dependent replicative DNA synthesis in permeable cell systems as well as in cellophane disk lysates[4]. It also inhibits bacterial DNA gyrase but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 g/ml
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化学信息
| 名称 | Oxolinic acid |
|---|---|
| Iupac 化学名称 | Oxolinic acid |
| 同义词 | Urinox, NSC 110364 |
| 英文同义词 | Urinox, NSC 110364 |
| 分子式 | C13H11NO5 |
| 分子量 | 261.23 |
| Smile | CCN1C=C(C(=O)C=2C1=CC1=C(C2)OCO1)C(=O)O |
| InChiKey | KYGZCKSPAKDVKC-UHFFFAOYSA-N |
| InChi | InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17) |
| Cas号 | 14698-29-4 |
| 相关CAS号 |
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